Curaden introduces new Perio plus zero

Curaden

Tue. 4 February 2025

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DUBAI, UAE/KRIENS, Switzerland: The oral microbiome is essential for overall health, but traditional antiseptics like chlorhexidine can disrupt its balance. Perio plus zero by Curaprox introduces a groundbreaking approach, offering effective antibacterial protection while preserving the microbiome’s natural harmony. The product is currently on display at AEEDC Dubai 2025.

Rooted in advanced microbiome research, this innovative formula sets a new standard in oral care by safeguarding oral health without compromise. Attracting growing interest from universities and scientists, Perio plus zero represents the future of dentistry—a gentle yet powerful solution poised to transform oral hygiene practices.

A new approach to oral antiseptics

The mouth is one of the body’s most intricate ecosystems, home to over 700 species of bacteria and an astonishing 750 million microorganisms per millilitre of saliva. This complex microbiome plays a crucial role in fending off pathogens and preserving oral health. Conventional mouthwashes have long relied on chlorhexidine, a powerful antiseptic that often causes side effects like taste alteration, staining and microbiome disruption. New antiseptics such as Perio plus zero feature clever formulations that combine effectiveness with preserving the oral microbiome’s delicate balance.

Perio plus zero’s secret lies in its combination of Citrox, a plant-derived extract, with the antiseptic cetylpyridinium chloride at a carefully calibrated concentration, containing less of this compound than most traditional mouthwashes. This precise formulation ensures potent antibacterial protection while minimising disruption to the intricate ecosystem of the mouth, respecting its natural harmony

Perio plus zero is the latest addition to the Curaprox Perio plus line of mouthwashes.

A new solution to an old problem

Central to bacterial activity in the mouth is quorum sensing, a system of chemical communication that coordinates behaviours such as biofilm formation and toxin release. Disrupting this communication, a process known as quorum quenching is emerging as a forward-thinking strategy to inhibit harmful bacteria while leaving their beneficial counterparts intact.

Citrox, extracted from citrus bioflavonoids, has gained attention for its antimicrobial properties. Recent research shows that it can disrupt quorum sensing, blocking harmful bacteria from forming biofilms or releasing toxins. This makes Citrox not just an antibacterial agent but a quorum quencher, selectively targeting problematic bacteria while preserving the beneficial ones essential for oral health.

Citrox enhances the formula’s antibacterial efficacy, providing long-lasting protection against pathogens without the disruptive side effects of traditional antiseptics. This breakthrough represents a significant advancement in oral hygiene science, marrying ingenuity with modern technology.

From disruption to balance

Perio plus zero challenges the status quo by prioritising the preservation of the oral microbiome while delivering effective protection against harmful bacteria. Its formula—which is also non-staining and free of alcohol and sodium lauryl sulfate—is suitable for both short- and long-term use, whether before or after dental procedures.

Designed with the latest microbiome-focused science in mind, the formula ensures antibacterial substantivity, offering extended protection long after use. By targeting pathogenic bacteria with precision, Perio plus zero aligns with a growing movement in oral care—one that recognises the importance of balance over brute force.

Visit Curaden at Booth CC25 during AEEDC Dubai to learn about Perio plus zero, or find more details here.